Excessive and chronic alcohol consumption has been shown to have a toxic effect on the intestines, impairing the absorption of Vitamin B1. As such, many people who have abused alcohol develop LowB1. This can cause numbness, tingling, burning, and/or shooting pains in their feet and legs. It can also cause impaired functioning of the brain. The use of a high-potency bioactive form of Vitamin B1 has been shown to improve both numbness, tingling, burning, and/or shooting pains in the feet and legs and brain function in people who have abused alcohol excessively over long periods of time.*